Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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Please review our privacy policy. With this approach, we studied the antimicrobial activity of CE of A. View at Google Scholar J.

Images were obtained at 10 and 40x magnification ampphipterygium and c. The distinguishing factor of this tree is its bark. This observation suggests that A. As for activity of A.

Amphipterygium adstringens – Wikipedia

Using the concentration-response curve for each cell line, total growth inhibition TGI was defined as the concentration value that produces total growth inhibition and was determined by nonlinear regression analysis using the software Origin 7.

The authors declare that there is no conflict of interests regarding the publication of this paper.

The scoring system yields minimal and maximal total scores of 0 and 9. In this regard, the use of alternative therapies has emerged as a common approach in gastrointestinal diseases; actually, studies describe that almost half of IBD patients have ever taken or currently use complementary remedies [ 56 ]. A wide range of uses and diversity of biological activities reported reminds us of a complex mixture of multitarget compounds, which is a common characteristic in several medicinal plants and similar to others [ 22 ].

Those are the lowest among all MIC values shown in our data, suggesting that A. Green tea catechin, epigallocatechingallate EGCG: As mentioned before, oral microbiota diversity is closely related to health conditions and systemic diseases such as cardiovascular and inflammatory diseases and cancer.

Cytotoxic avstringens and effect on nitric oxide production of tirucallane-type triterpenes. An examiner without prior knowledge of experimental procedures scored the degree of colitis. Another important group of compounds present in the A. Supplemental naringenin prevents intestinal barrier defects and inflammation in colitic mice.


According to literature, phenols are the main responsible compounds amphipteygium the antioxidant activity [ 24 ]; for this reason, the AaEE has been analyzed.

Evidence-Based Complementary and Alternative Medicine

Experimental colitis models have been used to identify therapeutic agents and elucidate the underlying physiologic mechanisms of UC. Published online Aug This bark is believed to cure malaria, stomach cancer, gastric ulcers and kidney sicknesses. After the solvent-solvent extraction, the hexane fraction F 1 was amphlpterygium from the AaEE. This article has been cited by other articles in PMC. With respect to IL, this cytokine contributes to the differentiation of regulatory T cells Tregwhile suppressing dendritic cell-associated Th1 and Th17 immunity, as well as regulating inflammatory responses [ 36 adsrtingens, 37 ].

European Journal of Pharmacology. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are bacteria often isolated from the subgingival biofilm [ 3031 ] and associated with periodontitis and gingivitis.

View at Google Adstringena H.

Colonic Antioxidant Enzyme Activities of AaEE The activity of antioxidant enzymes in colonic tissues of control and experimental group of mice is shown in Figure 4. Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens bark was obtained by Dr.

The standard treatments for colitis are generally immunosuppressant and anti- inflammatory drugs, which have many undesirable side effects. By using this site, you agree to the Terms of Use and Privacy Policy. Antimicrobial activity of northwestern mexican plants against Helicobacter pylori. Amphipterygium adstringens Diederich Franz Leonhard von Schlechtendal. Use of medicinal plants in Monterrey, Mexico. Subscribe to Table of Contents Alerts. Oxidative stress is one of the most crucial factors causing UC.

We investigated the effects of alcoholic extract of A. Effect of 6-nonadecyl salicylic acid and its methyl ester on the induction of micronuclei in polychromatic erythrocytes in mouse peripheral blood.

The presence of hydroxyl groups in the structure also enhances the inhibition of lipid peroxidation [ 4041 ]. Microbial species in oral cavity are commensals under normal physiological conditions.


Journal of Agricultural and Food Chemistry.

Amphipterygium adstringens – Useful Tropical Plants

Because of its ever-growing popularity and since the most sought after amphipteryigum of the plant is its bark, the cuachalalate was as of considered an endangered species. In this study, we showed that AaEE inhibited experimental colitis, resulting in overall attenuation of inflammation DAI, including colon length and body weight changes.

The colon length was It is an effective antiplaque agent developed to date, but it has been proven that prolonged use ampgipterygium several undesirable side effects; besides many clinical trials have shown that taste of chlorhexidine is not well accepted by children [ 52 ]. Views Read Edit View history.

Principles of the bark of Amphipterygium adstringens (Julianaceae) with anti-inflammatory activity.

Table of Contents Alerts. This can be mainly related to their safety, since they have been taken from ancient times, in addition to their reputed efficacy, most probably due to the presence of different active components that can concurrently target several pathways or mediators of the inflammatory response.

EGCG reduces experimental colon injury by inhibiting macrophage chemotaxis toward N-formyl-L-leucyl-L-phenylalanine, thereby suppressing the mast cells and macrophage activities [ 43 ]. Nevertheless the CE itself is useful in the development of new antimicrobial treatment based on natural products to prevent oral diseases and as alternative natural source for cancer treatment and prevention.

View at Google Scholar I. Compared to control mice, DSS mice showed significantly amphipterygiuk histopathological scoring of disease Figure 3 a.

Mauricio Gonzalez, following the amlhipterygium revision of the genus Amphipterygium Julianaceae [ 46 ]. Whole plant and bark of Amphipterygium adstringens growing in Michoacan, Mexico.