and pharmacological properties of Kigelia africana (Lam.) Balmkheera, Isopinnatal, Kigelin, Chemical constituents, Medicinal properties. Objective: Kigelia africana, a tropical tree, which has long been used in African . Analytical grade solvents (Fischer chemicals) were used for isolation and. cancer with drugs (pharmacotherapy) or with chemical compounds ( chemotherapy) in family comprises 21 species, of which Kigelia africana. (Lam. ) Benth is.

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Stuppner H, Wagner H. Hexane, petroleum spirit, dichloromethane, ethyl acetate, methanol and ethanol used were analytical, while silica gel F and chemicaps spray reagent were obtained from the chemical store of the Department of Chemistry, University of Ilorin, Nigeria. Related articles Anticryptoccocal antileishmanial cannabinoid receptors Kigelia africana opioid receptors.

Flavonoids, a class of natural products of high pharmacological potency. Further, the results cuemicals the in vitro assays corroborate the traditional utility of this plant in medicine. The tree grows on riverbanks, wet areas along streams and on flood plains of Nigeria, Cameroon, Kenya, Guinea and Senegal.

New Constituents of Kigelia pinnata Leaves – SciAlert Responsive Version

Trans fatty acids and cardiovascular risk. Special attention may have to be paid to the extraction method. Anticryptoccocal, antileishmanial, cannabinoid receptors, Kigelia africana, opioid receptors.

It is a Phenylpropanoid and phenylethanoid derivatives from Kigelia pinnata D. Phenylpropanoid and phenylethanoid derivatives from Kigelia pinnata DC. Pharm Pharmacol Africaa ;7: Advanced Search Users Online: The major pot afforded 1,3,3,5,6,6-hexamethylcyclohexa-1,4-diene VI with R f value; 0.


The powdered plant material g was exhaustively extracted with n-hexane at room temperature for six days to afford 3.

Long-term treatment with Kigelia pinnata fruit extract ameliorates the testicular toxicity following cisplatin administration in male Sprague-Dawley rats. Simultaneously hermaphroditic shrimp use lipophilic cuticular hydrocarbons as contact sex pheromones. The africwna powers of the extracts were evaluated according to the method of Oyaizu [ 40 ].

The chloroform extract exhibited substantial antileishmanial activity of Leishmania donovani.

None, Chemixals of Interest: The antioxidant potential of the oil was compared to that of ethyl acetate and methanol extracts of the root. Free radical scavenging capacity in the ageing of selected red Spanish wines. The ethyl acetate extract showed the same activity.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

Antibacterial and antifungal compounds from Kigelia pinnata. Cassell and Collier Chemocals Publ; The structures of phenolic compounds which exhibited antioxidant activity in the ethyl acetate fraction would need to be elucidated.

Novel lapachol derivatives and their antioxidant activity. Preparative thin layer chromatography. World J Tradit Chin Med ;3: The combined fractions 10 klgelia 13 was chromatographed on a preparative silica gel TLC plates eluted with a 5: In vitro cytotoxicity of norviburtinal and isopinnatal from Kigelia pinnata against cancer cell lines.


Prostaglandins Leukot Essent Fatty Acids. Compound IV is a well known natural product and was easily identified by comparing its physical propertiesinfrared spectrum and mass spectrum with data from literature. The extract was found effective when tested against melanoma cells a tumour of pigmented skin cells by inhibiting the growth of cultured melanoma cells chemlcals Houghton et al.

Lately, it has been reported that incorporation of kigellia fatty acids into the phospholipids of the membranes affected its properties and mainly the activity of enzymes attached to the membrane, in fact, in recent times a positive relation has been established between allergic diseases and trans fatty acid consumption Kritchevsky, [ 26 ]; Stender and Dyerberg, [ chenicals ].

A procedure to measure the antiradical efficiency of polyphenols. Anti-inflammatory activity of verminoside from Kigelia africana and evaluation of cutaneous irritation in cell cultures and reconstituted human epidermis.

Deletion of the cyclin-dependent kinase-4 inhibitor gene inmultiple human cancers. Helvetica Chimica Acta, Interestingly, methyl linoleate, has been used to reduce soft scald of apple Wills et al. It is predicted that compound IV may be a precursor to the biosynthesis of phytol. Afrciana stress and neurodegeneration: Fetal growth in rats treated with lapachol.